hic-loop-calling
This skill performs chromatin loop detection from Hi-C .mcool files using cooltools.
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This skill performs chromatin loop detection from Hi-C .mcool files using cooltools.
This skill performs protein-mediated regulatory community analysis from ChIA-PET datasets and provide a way for visualizing the communities. Use this skill when you have a annotated peak file (in BED format) fr...
This skill performs genome-wide DNA methylation profiling. It supports single-sample and multi-sample workflows to compute methylation density distributions, genomic feature distribution of the methylation prof...
This skill performs differential DNA methylation analysis (DMRs and DMCs) between experimental conditions using WGBS methylation tracks (BED/BedGraph). It standardizes input files into per-sample four-column Me...
This skill should be used when users need to identify topologically associating domains (TADs) from Hi-C data in .mcools (or .cool) files or when users want to visualize the TAD in target genome loci. It provid...
This skill performs standardized quality control (QC) on Hi-C contact matrices stored in .mcool or .cool format. It computes coverage and cis/trans ratios, distance-dependent contact decay (P(s) curves), covera...
This skill provides a complete pipeline for integrating CpG methylation data with chromatin features such as ATAC-seq signal, H3K27ac, H3K4me3, or other histone marks/TF signals.
This skill performs A/B compartment shift analysis between two Hi-C samples.
The differential-region-analysis pipeline identifies genomic regions exhibiting significant differences in signal intensity between experimental conditions using a count-based framework and DESeq2. It supports...
This skill generates normalized BigWig (.bw) tracks (and/or fold-change tracks) from BAM files for ATAC-seq and ChIP-seq visualization. It handles normalization (RPM or fold-change) and Tn5 offset correction au...
This skill identifies novel transcription factor binding motifs in the promoter regions of genes, or directly from genomic regions of interest such as ChIP-seq peaks, ATAC-seq accessible sites, or differentiall...
This skill performs transcription factor (TF) footprint analysis using TOBIAS on ATAC-seq data. It corrects Tn5 sequence bias, quantifies TF occupancy at motif sites, generates footprint scores, and optionally...
The TF-differential-binding pipeline performs differential transcription factor (TF) binding analysis from ChIP-seq datasets (TF peaks) using the DiffBind package in R. It identifies genomic regions where TF bi...
This pipeline performs genome-wide segmentation of CpG methylation profiles to identify Unmethylated Regions (UMRs), Low-Methylated Regions (LMRs), and Partially Methylated Domains (PMDs) using whole-genome bis...
Authenticate with Jira Cloud REST API using API tokens. Use when setting up Jira connections, validating credentials, or handling rate limiting.
Create, read, update, and delete Jira issues. Use when managing Stories, Tasks, Bugs, or Epics - includes field updates and metadata.
Move Jira issues through workflow states. Use when transitioning issues (To Do, In Progress, Done) or setting resolutions.
Administer Jira projects. Use when creating/archiving projects, managing components, versions, roles, permissions, or project configuration.
Manage Jira Agile boards and sprints. Use when listing boards, creating sprints, or moving issues to/from sprints.
Manage Jira projects. Use when listing projects, getting project configuration, retrieving issue types, or managing components and versions.
Search Jira issues using JQL queries. Use when filtering issues by project, status, assignee, date, or building reports.
Manage Confluence spaces for project documentation. Create, list, and delete spaces with templates. Use when setting up project documentation structure or managing Confluence content areas.
Answer questions about Speck specs, plans, tasks, requirements, progress, architecture, user stories, feature status, and constitution. Interprets spec.md, plan.md, tasks.md files. Use when users ask about feat...
Review GitHub pull requests with VSCode integration. Use when the user asks to "review a PR", "review PRs", "check pull requests", or wants AI-assisted code review with clickable navigation and one-click commen...
Le classement utilise les étoiles du dépôt GitHub indexé. Plusieurs skills peuvent partager ce nombre : ce n’est ni un nombre d’installations ni une note de qualité.