differential-region-analysis

Fonctions et usage

The differential-region-analysis pipeline identifies genomic regions exhibiting significant differences in signal intensity between experimental conditions using a count-based framework and DESeq2. It supports detection of both differentially accessible regions (DARs) from open-chromatin assays (e.g., ATAC-seq, DNase-seq) and differential transcription factor (TF) binding regions from TF-centric assays (e.g., ChIP-seq, CUT&RUN, CUT&Tag). The pipeline can start from aligned BAM files or a precomputed count matrix and is suitable whenever genomic signal can be summarized as read counts per region.

Démarrage rapide

Suivez les instructions du dépôt pour votre agent. Consultez les fichiers et dépendances avant l’installation.