hic-matrix-qc

Fonctions et usage

This skill performs standardized quality control (QC) on Hi-C contact matrices stored in .mcool or .cool format. It computes coverage and cis/trans ratios, distance-dependent contact decay (P(s) curves), coverage uniformity, and replicate correlation at a chosen resolution using cooler and cooltools. Use it to assess whether Hi-C data are of sufficient quality for downstream analyses such as TAD calling, loop detection, and compartment analysis.

Démarrage rapide

Suivez les instructions du dépôt pour votre agent. Consultez les fichiers et dépendances avant l’installation.