探索开发、内容、数据与办公效率等 AI 技能。先比较用途和仓库热度，再查看技能说明与来源。
The differential-region-analysis pipeline identifies genomic regions exhibiting significant differences in signal intensity between experimental conditions using a count-based framework and DESeq2. It supports...
This skill generates normalized BigWig (.bw) tracks (and/or fold-change tracks) from BAM files for ATAC-seq and ChIP-seq visualization. It handles normalization (RPM or fold-change) and Tn5 offset correction au...
This skill identifies novel transcription factor binding motifs in the promoter regions of genes, or directly from genomic regions of interest such as ChIP-seq peaks, ATAC-seq accessible sites, or differentiall...
This skill performs transcription factor (TF) footprint analysis using TOBIAS on ATAC-seq data. It corrects Tn5 sequence bias, quantifies TF occupancy at motif sites, generates footprint scores, and optionally...
The TF-differential-binding pipeline performs differential transcription factor (TF) binding analysis from ChIP-seq datasets (TF peaks) using the DiffBind package in R. It identifies genomic regions where TF bi...
This pipeline performs genome-wide segmentation of CpG methylation profiles to identify Unmethylated Regions (UMRs), Low-Methylated Regions (LMRs), and Partially Methylated Domains (PMDs) using whole-genome bis...
Authenticate with Jira Cloud REST API using API tokens. Use when setting up Jira connections, validating credentials, or handling rate limiting.
Create, read, update, and delete Jira issues. Use when managing Stories, Tasks, Bugs, or Epics - includes field updates and metadata.
Move Jira issues through workflow states. Use when transitioning issues (To Do, In Progress, Done) or setting resolutions.
Administer Jira projects. Use when creating/archiving projects, managing components, versions, roles, permissions, or project configuration.
Manage Jira Agile boards and sprints. Use when listing boards, creating sprints, or moving issues to/from sprints.
Manage Jira projects. Use when listing projects, getting project configuration, retrieving issue types, or managing components and versions.
Search Jira issues using JQL queries. Use when filtering issues by project, status, assignee, date, or building reports.
Manage Confluence spaces for project documentation. Create, list, and delete spaces with templates. Use when setting up project documentation structure or managing Confluence content areas.
Answer questions about Speck specs, plans, tasks, requirements, progress, architecture, user stories, feature status, and constitution. Interprets spec.md, plan.md, tasks.md files. Use when users ask about feat...
Review GitHub pull requests with VSCode integration. Use when the user asks to "review a PR", "review PRs", "check pull requests", or wants AI-assisted code review with clickable navigation and one-click commen...
Hidden automatic debugging when something breaks - user sees simple question or "fixing..." not stack traces or technical errors
Language-agnostic backend patterns: API design, authentication, security, databases. Use when: designing APIs, implementing auth, securing endpoints, modeling data. Triggers: "api design", "rest api", "graphql"...
Learn Claude Code in 5 hands-on lessons. From basics to building applications. Use when: user wants to learn Claude Code, asks "how do I...", or is new. Triggers: "learn", "teach me", "how does this work", "I'm...
Identify performance bottlenecks systematically. Measure before optimizing.
Mobile UI patterns, gestures, animations, and platform-specific design.
Logs architectural decisions to docs/DECISIONS.md in ADR format. Use when: making significant architectural or technology choices. Integrates with /craft and /why commands.
Build Telegram bots with modern frameworks. Use when: creating Telegram bot, chatbot, notification bot. Triggers: "telegram", "tg bot", "телеграм бот", "teloxide", "aiogram".
Create distinctive, production-grade frontend interfaces avoiding "AI slop" aesthetics. Use when: building landing pages, dashboards, components, or styling any web UI. Triggers: "design", "landing page", "beau...
默认按已收录数据中的 GitHub 仓库 Stars 排序。Stars 属于来源仓库，同一仓库的多个技能可能共享相同数值；它反映仓库关注度，不代表单个技能的安装量或质量评分。