metabolicexpimputation
Imputes missing/dropout values in scRNA-seq expression data to improve metabolic pathway analysis. This process handles sparsity common in single-cell RNA sequencing data by filling in zero values using advance...
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Imputes missing/dropout values in scRNA-seq expression data to improve metabolic pathway analysis. This process handles sparsity common in single-cell RNA sequencing data by filling in zero values using advance...
Annotates cell clusters with biological cell type labels using multiple methods: direct assignment, ScType, scCATCH, hitype, or CellTypist. This process is essential for interpreting clustering results by assig...
Comprehensive metabolic landscape analysis pipeline for scRNA-seq data. This is an all-in-one process group performing complete metabolic pathway analysis including expression imputation, feature selection, pat...
Performs coarse clustering on ALL cells (including T cells, B cells, and non-T/B cells) before cell type selection. This process identifies broad cell populations to enable subsequent T/B cell selection via `TO...
Finds marker genes for clusters of ALL cells before T/B cell selection. This process identifies differentially expressed genes across unsupervised clusters to help identify broad cell types (T cells, B cells, M...
Finds differentially expressed genes (markers) for clusters of T/B cells using Seurat's FindMarkers function. Performs statistical testing between clusters, identifies cluster-defining genes, and automatically...
Performs pseudo-bulk differential gene expression analysis using DESeq2 or edgeR. Aggregates single-cell counts to sample-level pseudo-bulk data, then identifies differentially expressed genes between condition...
Analyzes metabolic pathway heterogeneity within cell populations by calculating normalized enrichment scores (NES) for each pathway across different groups. Quantifies metabolic diversity and identifies pathway...
Infer ligand-receptor interactions and cell-cell communication networks from single-cell RNA-seq data using the LIANA+ framework. Identifies potential signaling events between cell types based on gene expressio...
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Rust 技能索引。提供所有技能的快速导航和查询入口。触发词:skill, index, 技能, 索引, 目录
Comprehensive vitest testing patterns covering test structure, AAA pattern, parameterized tests, assertions, mocking, test doubles, error handling, async testing, and performance optimization. Use when writing,...
性能优化专家。处理 benchmark, profiling, allocation, SIMD, cache, 优化, 基准测试等问题。触发词:performance, optimization, benchmark, profiling, allocation, SIMD, cache, make it faster, 性能优化, 基准测试, 内存...
嵌入式 C 代码风格助手。基于 51 单片机例程学习的代码规范, 用于创建项目和优化代码。
高级生命周期专家。处理 HRTB, GAT, 'static 约束, dyn trait object, 泛型边界冲突等问题。触发词:lifetime, HRTB, GAT, 'static, dyn, trait object, one type is more general, 生命周期, 类型约束
并发与异步专家。处理 Send, Sync, thread, async, await, tokio, channel, Mutex, deadlock, race condition, 并发, 异步, 死锁等问题。触发词:thread, spawn, channel, mpsc, Mutex, RwLock, Atomic, async, await, Future,...
高级异步模式专家。处理 Stream 实现, 零拷贝, tokio::spawn 生命周期, 插件系统调度, tonic 流式响应等问题。触发词:async, Stream, tokio::spawn, 零拷贝, 插件系统, tonic, 流式, BorrowedMessage, 异步调度
类型驱动设计专家。处理 newtype, type state, PhantomData, marker trait, builder pattern, 类型状态, 新类型模式, 编译时验证, sealed trait, ZST
可变性专家。处理 E0596, E0499, E0502, interior mutability, Cell, RefCell, Mutex, RwLock, borrow conflict, 可变性, 内部可变性, 借用冲突
高级异步模式专家。处理 Stream, backpressure, select, join, cancellation, Future trait 等问题。触发词:async, Stream, backpressure, select, Future, tokio, async-std, 异步, 流, 取消
深入错误处理专家。处理 Result vs Option, thiserror, anyhow, error context, library vs application errors, 错误处理, Result 用法, 什么时候用 panic
Rust 生态专家。处理 crate 选择、库推荐、框架对比、async runtime 选择、序列化库、web 框架等。触发词:crate, library, framework, ecosystem, async runtime, tokio, async-std, serde, reqwest, axum, 库, 框架, 生态
React performance optimization and best practices. Use when writing React components, hooks, or JSX; refactoring React code; optimizing re-renders, memoization, or state management; reviewing React code for per...
Rust Web 开发专家。处理 axum, actix, HTTP, REST, API, 数据库, 状态管理等问题。触发词:web, HTTP, REST, API, axum, actix, handler, database, web开发, 服务器, 路由
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