GitHub
binder-design
Guidance for choosing the right protein binder design tool. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs bet...
☆ 91查看技能
区块链 AI 技能
发现 区块链 相关 Skills，比较来源仓库和用途，查看适合你工作流的技能说明。
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GitHub
alphafold
Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence...
☆ 91查看技能
GitHub
bindcraft
End-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using different desi...
☆ 91查看技能
GitHub
esm
ESM2 protein language model for embeddings and sequence scoring. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) scores, (2) Getting protein embeddings for clustering, (3) Filtering designs by se...
☆ 91查看技能
GitHub
protein-design-workflow
End-to-end guidance for protein design pipelines. Use this skill when: (1) Starting a new protein design project, (2) Need step-by-step workflow guidance, (3) Understanding the full design pipeline, (4) Plannin...
☆ 91查看技能
GitHub
proteinmpnn
Design protein sequences using ProteinMPNN inverse folding. Use this skill when: (1) Designing sequences for RFdiffusion backbones, (2) Redesigning existing protein sequences, (3) Fixing specific residues while...
☆ 91查看技能
GitHub
rfdiffusion
Generate protein backbones using RFdiffusion, a diffusion-based generative model for de novo protein structure generation. Use this skill when: (1) Designing binder scaffolds for a target protein, (2) Generatin...
☆ 91查看技能
GitHub
uniprot
Access UniProt for protein sequence and annotation retrieval. Use this skill when: (1) Looking up protein sequences by accession, (2) Finding functional annotations, (3) Getting domain boundaries, (4) Finding h...
☆ 91查看技能
GitHub
ipsae
Binder design ranking using ipSAE (interprotein Score from Aligned Errors). Use this skill when: (1) Ranking binder designs for experimental testing, (2) Filtering BindCraft or RFdiffusion outputs, (3) Comparin...
☆ 91查看技能
GitHub
boltzgen
All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusion (not ju...
☆ 91查看技能
GitHub
protein-qc
Quality control metrics and filtering thresholds for protein design. Use this skill when: (1) Evaluating design quality for binding, expression, or structure, (2) Setting filtering thresholds for pLDDT, ipTM, P...
☆ 91查看技能
GitHub
solublempnn
Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4...
☆ 91查看技能
GitHub
cell-free-expression
Guidance for cell-free protein synthesis (CFPS) optimization. Use when: (1) Planning CFPS experiments, (2) Troubleshooting low yield or aggregation, (3) Optimizing DNA template design for CFPS, (4) Expressing d...
☆ 91查看技能
GitHub
ligandmpnn
Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coord...
☆ 91查看技能
GitHub
foldseek
Structure similarity search with Foldseek. Use this skill when: (1) Finding similar structures in PDB/AFDB databases, (2) Structural homology search, (3) Database queries by 3D structure, (4) Finding remote hom...
☆ 91查看技能
GitHub
boltz
Structure prediction using Boltz-1/Boltz-2, an open biomolecular structure predictor. Use this skill when: (1) Predicting protein complex structures, (2) Validating designed binders, (3) Need open-source altern...
☆ 91查看技能
GitHub
initiate-memory
Comprehensive guide for initializing or reorganizing agent memory and project context. Use when setting up a new project, when the user asks you to learn about the codebase, or when you need to create effective...
☆ 91查看技能
GitHub
dspy-agent-framework-quick-ref
Quick reference card for DSPy + Agent Framework integration patterns: typed signatures, assertions, routing cache, and agent handoffs.
☆ 91查看技能
GitHub
system-learn
Ingest new procedural memory (skills, patterns, docs) into the vector database.
☆ 91查看技能
GitHub
reflect
Analyze the current session and consolidate learnings. Use at the end of a session or task.
☆ 91查看技能
GitHub
recall
Semantic search for memory. Use to find solutions, patterns, or context from Chroma Cloud.
☆ 91查看技能
GitHub
memory-system
Complete guide to the AgenticFleet memory system. Read this first.
☆ 91查看技能
GitHub
fleet-agent
Context-aware development assistant for AgenticFleet with auto-learning and dual memory (NeonDB + ChromaDB). Handles development workflows with intelligent context management.
☆ 91查看技能
GitHub
system-init
Initialize or hydrate the agent's memory system and verify configuration.
☆ 91查看技能
默认按已收录数据中的 GitHub 仓库 Stars 排序。Stars 属于来源仓库，同一仓库的多个技能可能共享相同数值；它反映仓库关注度，不代表单个技能的安装量或质量评分。