datamol
Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery including SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conforme...
Skills matching the name, description or GitHub author.
Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery including SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conforme...
MATLAB and GNU Octave numerical computing for matrix operations, data analysis, visualization, and scientific computing. Use when writing MATLAB/Octave scripts for linear algebra, signal processing, image proce...
Direct REST API access to UniProt. Protein searches, FASTA retrieval, ID mapping, Swiss-Prot/TrEMBL. For Python workflows with multiple databases, prefer bioservices (unified interface to 40+ services). Use thi...
Framework for computational fluid dynamics simulations using Python. Use when running fluid dynamics simulations including Navier-Stokes equations (2D/3D), shallow water equations, stratified flows, or when ana...
Python library for working with geospatial vector data including shapefiles, GeoJSON, and GeoPackage files. Use when working with geographic data for spatial analysis, geometric operations, coordinate transform...
High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection, tokenization for ML models, or fragment...
Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.
Process-based discrete-event simulation framework in Python. Use this skill when building simulations of systems with processes, queues, resources, and time-based events such as manufacturing systems, service o...
Specialized skill for building production-ready Discord bots. Covers Discord.js (JavaScript) and Pycord (Python), gateway intents, slash commands, interactive components, rate limiting, and sharding.
Expert patterns for HubSpot CRM integration including OAuth authentication, CRM objects, associations, batch operations, webhooks, and custom objects. Covers Node.js and Python SDKs. Use when: hubspot, hubspot...
Expert patterns for Azure Functions development including isolated worker model, Durable Functions orchestration, cold start optimization, and production patterns. Covers .NET, Python, and Node.js programming m...
Build Slack apps using the Bolt framework across Python, JavaScript, and Java. Covers Block Kit for rich UIs, interactive components, slash commands, event handling, OAuth installation flows, and Workflow Build...
IDA Pro Python scripting for reverse engineering. Use when writing IDAPython scripts, analyzing binaries, working with IDA's API for disassembly, decompilation (Hex-Rays), type systems, cross-references, functi...
Python development principles and decision-making. Framework selection, async patterns, type hints, project structure. Teaches thinking, not copying.
Interactive Python REPL automation with common helpers and best practices
This skill should be used when the user wants to visualize data. It intelligently selects the most suitable chart type from 26 available options, extracts parameters based on detailed specifications, and genera...
Build Python agents with Agentica SDK - @agentic decorator, spawn(), persistence, MCP integration
Atheris is a coverage-guided Python fuzzer based on libFuzzer. Use for fuzzing pure Python code and Python C extensions.
Detects timing side-channel vulnerabilities in cryptographic code. Use when implementing or reviewing crypto code, encountering division on secrets, secret-dependent branches, or constant-time programming quest...
Guide for creating high-quality MCP (Model Context Protocol) servers that enable LLMs to interact with external services through well-designed tools. Use when building MCP servers to integrate external APIs or...
Search arXiv preprint repository for papers in physics, mathematics, computer science, quantitative biology, and related fields, Instructions for searching arXiv papers using Python script and shell tool. Read...
Comprehensive guide for porting UI components from R's bslib package to py-shiny. Use this skill when: (1) User asks to "port this feature" or "port a component" and mentions bslib or links to a bslib PR (e.g.,...
Build robust backend systems with modern technologies (Node.js, Python, Go, Rust), frameworks (NestJS, FastAPI, Django), databases (PostgreSQL, MongoDB, Redis), APIs (REST, GraphQL, gRPC), authentication (OAuth...
Build AI applications using the Azure AI Projects Python SDK (azure-ai-projects). Use when working with Foundry project clients, creating versioned agents with PromptAgentDefinition, running evaluations, managi...
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