GitHub
esm
Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use...
☆ 26View skill
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GitHub
chembl-database
Query ChEMBL's bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.
☆ 26View skill
GitHub
cosmic-database
Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication.
☆ 26View skill
GitHub
dnanexus-integration
DNAnexus cloud genomics platform. Build apps/applets, manage data (upload/download), dxpy Python SDK, run workflows, FASTQ/BAM/VCF, for genomics pipeline development and execution.
☆ 26View skill
GitHub
ensembl-database
Query Ensembl genome database REST API for 250+ species. Gene lookups, sequence retrieval, variant analysis, comparative genomics, orthologs, VEP predictions, for genomic research.
☆ 26View skill
GitHub
drugbank-database
Access and analyze comprehensive drug information from the DrugBank database including drug properties, interactions, targets, pathways, chemical structures, and pharmacology data. This skill should be used whe...
☆ 26View skill
GitHub
medchem
Medicinal chemistry filters. Apply drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, complexity metrics, for compound prioritization and library filtering.
☆ 26View skill
GitHub
matchms
Mass spectrometry analysis. Process mzML/MGF/MSP, spectral similarity (cosine, modified cosine), metadata harmonization, compound ID, for metabolomics and MS data processing.
☆ 26View skill
GitHub
datamol
Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery: SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, paral...
☆ 26View skill
GitHub
pymatgen
Materials science toolkit. Crystal structures (CIF, POSCAR), phase diagrams, band structure, DOS, Materials Project integration, format conversion, for computational materials science.
☆ 26View skill
GitHub
astropy
Astronomy toolkit. FITS I/O, celestial coordinate transforms, cosmology calculations, time systems, WCS, units, astronomical tables, for astronomical data analysis and imaging.
☆ 26View skill
GitHub
histolab
Digital pathology image processing toolkit for whole slide images (WSI). Use this skill when working with histopathology slides, processing H&E or IHC stained tissue images, extracting tiles from gigapixel path...
☆ 26View skill
GitHub
etetoolkit
Phylogenetic tree toolkit (ETE). Tree manipulation (Newick/NHX), evolutionary event detection, orthology/paralogy, NCBI taxonomy, visualization (PDF/SVG), for phylogenomics.
☆ 26View skill
GitHub
anndata
Manipulate AnnData objects for single-cell genomics. Load/save .h5ad files, manage obs/var metadata, layers, embeddings (PCA/UMAP), concatenate datasets, for scRNA-seq workflows.
☆ 26View skill
GitHub
pathml
Computational pathology toolkit for analyzing whole-slide images (WSI) and multiparametric imaging data. Use this skill when working with histopathology slides, H&E stained images, multiplex immunofluorescence...
☆ 26View skill
GitHub
b2c-config
View and debug B2C CLI configuration and understand where credentials come from. Use when authentication fails, connection errors occur, wrong instance is used, or you need to verify dw.json settings, environme...
☆ 26View skill
GitHub
apr
Run APR (Automated Plan Reviser) workflow for FCP specification refinement. Use when asked to run APR, revision rounds, spec review, integrate GPT feedback, or harmonize docs. Handles Oracle remote setup, runni...
☆ 25View skill
GitHub
express-to-fastify-migration
Migrate Express.js REST APIs to Fastify with automated testing, performance benchmarking, and schema generation. Use when migrating Express applications to Fastify, modernizing Node.js APIs, improving API perfo...
☆ 25View skill
GitHub
private-connect
Access private services by name, from anywhere. No VPN or SSH tunnels.
☆ 25View skill
GitHub
prompt-tuner
Improve embedded LLM system prompt based on evaluation test failures
☆ 25View skill
GitHub
validate-constitution
Validates code changes against the project's consolidated knowledge and configuration rules. Use on push to catch violations of agreed-upon standards like installation scripts, linking patterns, and configurati...
☆ 25View skill
GitHub
caro-shell-helper
Use when users need help generating safe, tested POSIX shell commands from natural language descriptions. Guides users through command generation, safety validation, and execution workflows using Caro best prac...
☆ 25View skill
GitHub
beta-test-cycles
This skill should be used when the user asks to "run beta test cycle", "run next cycle", "test static patterns", "analyze test failures", "improve pass rate", or wants to systematically improve command generati...
☆ 25View skill
GitHub
quality-engineer-manager
Quality Engineer Manager skill for orchestrating release validation, beta testing coordination, feedback analysis, and release sign-off decisions
☆ 25View skill
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