Discover Business skills, compare source repositories and read the instructions for each workflow.
30 pragmatic rules for production JavaScript covering async operations, V8 optimization, memory management, testing, error handling, and performance. Use when writing JavaScript, optimizing performance, handlin...
Utopia.fyi fluid typography and spacing system using clamp(), modular scales, and proportional design. Use when implementing fluid type scales, space palettes, t-shirt sizing, space pairs, or creating fluid res...
Production observability with tracing, OpenTelemetry, and Prometheus metrics including structured logging, instrumented functions, distributed tracing, health checks, and request correlation. Use when adding lo...
Production patterns for Tokio 1.48.0 async runtime including task spawning, channels (mpsc, oneshot, broadcast, watch), synchronization primitives, graceful shutdown, and lifecycle management. Use when spawning...
Build web components using Custom Elements v1 API with Declarative Shadow DOM, attribute-driven state, handleEvent pattern, and zero DOM selection. Use when creating custom elements, extending built-in HTML ele...
Foundational Rust style conventions that apply universally to all Rust code. Covers import organization, naming conventions, and code formatting standards. This skill is automatically applied to all Rust implem...
Reusable component patterns for Maud including the Render trait, function components, parameterized components, layout composition, partials, and component organization. Use when building reusable UI elements,...
Perform code review using CodeRabbit. Must use this skill if instructed to perform a CodeRabbit review.
MUST use this skill when user asks to check/review PR comments, address reviewer feedback, fix review issues, or respond to code review. Fetches unresolved review comments from GitHub PR for the current branch.
Analyzes MVP codebases and recommends prioritized next steps for product development. Use when the user asks "what should I build next?", "how do I improve my MVP?", "what features should I add?", or needs guid...
Software testing
Chezmoi dotfile management expertise
Expert guidance on Neovim configuration, plugin management, lazy.nvim, LSP setup, and editor workflow optimization
Elixir programming
Lua programming and Neovim
This skill should be used when users need to infer chromatin states from histone modification ChIP-seq data using chromHMM. It provides workflows for chromatin state segmentation, model training, state annotati...
Perform GO and KEGG functional enrichment using HOMER from genomic regions (BED/narrowPeak/broadPeak) or gene lists, and produce R-based barplot/dotplot visualizations. Use this skill when you want to perform G...
This skill identifies the locations of known transcription factor (TF) binding motifs within genomic regions such as ChIP-seq or ATAC-seq peaks. It utilizes HOMER to search for specific sequence motifs defined...
This skill analyzes the local DNA methylation profiles around target genomic regions provide by user. Use this skill when you want to vasulize the average methylation profile around target regions (e.g. TSS, CT...
Automatically detect and normalize Hi-C data. Only .cool or .mcool file is supported. All .mcool files are then checked for existing normalization (supports bins/weight only) and balanced if none of the normali...
This skill is used to perform genomic feature annotation and visualization for any file containing genomic region information using Homer (Hypergeometric Optimization of Motif EnRichment). It annotates regions...
Performs data cleaning and removal operations. This skill takes a raw BAM and creates a new, "clean" BAM file by actively removing artifacts: mitochondrial reads, blacklisted regions, PCR duplicates, and unmapp...
This skill annotates chromatin loops, including enhancer/promoter assignments, CTCF-peak overlap. It automatically constructs enhancer and promoter sets when missing and outputs standardized loop categories.
Calculates technical mapping statistics for any aligned BAM file (ChIP or ATAC). It assesses the performance of the aligner itself by generating metrics on read depth, mapping quality, error rates, and read gro...
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