ligandmpnn
Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coord...
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Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coord...
Structure similarity search with Foldseek. Use this skill when: (1) Finding similar structures in PDB/AFDB databases, (2) Structural homology search, (3) Database queries by 3D structure, (4) Finding remote hom...
Structure prediction using Boltz-1/Boltz-2, an open biomolecular structure predictor. Use this skill when: (1) Predicting protein complex structures, (2) Validating designed binders, (3) Need open-source altern...
Comprehensive guide for initializing or reorganizing agent memory and project context. Use when setting up a new project, when the user asks you to learn about the codebase, or when you need to create effective...
Quick reference card for DSPy + Agent Framework integration patterns: typed signatures, assertions, routing cache, and agent handoffs.
Ingest new procedural memory (skills, patterns, docs) into the vector database.
Analyze the current session and consolidate learnings. Use at the end of a session or task.
Semantic search for memory. Use to find solutions, patterns, or context from Chroma Cloud.
Complete guide to the AgenticFleet memory system. Read this first.
Context-aware development assistant for AgenticFleet with auto-learning and dual memory (NeonDB + ChromaDB). Handles development workflows with intelligent context management.
Initialize or hydrate the agent's memory system and verify configuration.
Automatically creates user-facing changelogs from git commits by analyzing commit history, categorizing changes, and transforming technical commits into clear, customer-friendly release notes. Turns hours of ma...
Expert Python backend code reviewer that identifies over-complexity, duplicates, bad optimizations, and violations of best practices. Use when asked to review Python code quality, check for duplicate code, anal...
Comprehensive guide to integrating DSPy with Microsoft Agent Framework in AgenticFleet, covering typed signatures, assertions, routing cache, GEPA optimization, and agent handoffs.
Use at the start of a new session to read project docs, understand context, and see current state
Use when extracting reusable patterns, solutions, or knowledge from completed tasks into documentation
Use when requirements are unclear, multiple approaches exist, or you need to explore solutions before planning
Use when you need to understand existing code, find patterns, or explore the codebase before implementation
Use when committing code changes with proper conventional commit format and verification
Use when working with Knowns documentation - viewing, searching, creating, or updating docs
Use when reopening a completed task to add new requirements, fix issues, or extend functionality
Use when working on a Knowns task - take ownership, research, plan, implement, complete with proper tracking
Conduct pure research for YouTube video topics by analyzing competitors, identifying content gaps, and documenting strategic insights. Use when you need to research a video topic before planning. Produces conci...
Generate optimized YouTube video titles that maximize click-through rates by sparking curiosity and complementing thumbnails. This skill should be used when the user asks to create, improve, or brainstorm YouTu...
Le classement utilise les étoiles du dépôt GitHub indexé. Plusieurs skills peuvent partager ce nombre : ce n’est ni un nombre d’installations ni une note de qualité.