Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design, use proteinmpnn. For ligand-aware design, use ligandmpnn.
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Quick Start
TopRank Skills install adaptyvbio/solublempnn
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Skill Details
GitHub Stars
91
GitHub Forks
7
Created
Jan 2026
Last Updated
il y a 8 mois
tools
tools computational chemistry
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